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Select item 1068791.

Direct Sulfhydrylation for Methionine Biosynthesis in Leptospira meyeri

J. Belfaiza, A. Martel, D. Margarita, I. Saint Girons

J Bacteriol. 1998 Jan; 180(2): 250–255. doi: 10.1128/jb.180.2.250-255.1998

PMCID:: PMC106879

Article PDF–168K

Select item 65328422.

Revisiting the taxonomy and evolution of pathogenicity of the genus Leptospira through the prism of genomics

Antony T. Vincent, Olivier Schiettekatte, Cyrille Goarant, Vasantha Kumari Neela, Eve Bernet, Roman Thibeaux, Nabilah Ismail, Mohd Khairul Nizam Mohd Khalid, Fairuz Amran, Toshiyuki Masuzawa, Ryo Nakao, Anissa Amara Korba, Pascale Bourhy, Frederic J. Veyrier, Mathieu Picardeau

PLoS Negl Trop Dis. 2019 May; 13(5): e0007270. Published online 2019 May 23. doi: 10.1371/journal.pntd.0007270

PMCID:: PMC6532842

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Select item 65131093.

Genus-wide Leptospira core genome multilocus sequence typing for strain taxonomy and global surveillance

Julien Guglielmini, Pascale Bourhy, Olivier Schiettekatte, Farida Zinini, Sylvain Brisse, Mathieu Picardeau

PLoS Negl Trop Dis. 2019 Apr; 13(4): e0007374. Published online 2019 Apr 26. doi: 10.1371/journal.pntd.0007374

Correction in:: PLoS Negl Trop Dis. 2020 Aug; 14(8): e0008673.

PMCID:: PMC6513109

Article PDF–1.7M

Select item 42244234.

Sensitive Real-Time PCR Detection of Pathogenic Leptospira spp. and a Comparison of Nucleic Acid Amplification Methods for the Diagnosis of Leptospirosis

Jesse J. Waggoner, Ilana Balassiano, Janaki Abeynayake, Malaya K. Sahoo, Alisha Mohamed-Hadley, Yuanyuan Liu, Juliana Magalhães Vital-Brazil, Benjamin A. Pinsky

PLoS One. 2014; 9(11): e112356. Published online 2014 Nov 7. doi: 10.1371/journal.pone.0112356

PMCID:: PMC4224423

Article PDF–551K

Select item 54171915.

High-Resolution Melting Curve Analysis of the 16S Ribosomal Gene to Detect and Identify Pathogenic and Saprophytic Leptospira species in Colombian Isolates

Ronald G. Peláez Sánchez, Juan Álvaro López Quintero, Martha María Pereira, Piedad Agudelo-Flórez

Am J Trop Med Hyg. 2017 May 3; 96(5): 1031–1038. doi: 10.4269/ajtmh.16-0312

PMCID:: PMC5417191

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Select item 96398516.

Leptospira enrichment culture followed by ONT metagenomic sequencing allows better detection of Leptospira presence and diversity in water and soil samples

Myranda Gorman, Ruijie Xu, Dhani Prakoso, Liliana C. M. Salvador, Sreekumari Rajeev

PLoS Negl Trop Dis. 2022 Oct; 16(10): e0010589. Published online 2022 Oct 26. doi: 10.1371/journal.pntd.0010589

PMCID:: PMC9639851

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Select item 89703877.

Analysis of human clinical and environmental Leptospira to elucidate the eco-epidemiology of leptospirosis in Yaeyama, subtropical Japan

Yukuto Sato, Idam Hermawan, Tetsuya Kakita, Sho Okano, Hideyuki Imai, Hiroto Nagai, Ryosuke Kimura, Tetsu Yamashiro, Tadashi Kajita, Claudia Toma

PLoS Negl Trop Dis. 2022 Mar; 16(3): e0010234. Published online 2022 Mar 31. doi: 10.1371/journal.pntd.0010234

PMCID:: PMC8970387

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Select item 91541038.

Diverse lineages of pathogenic Leptospira species are widespread in the environment in Puerto Rico, USA

Nathan E. Stone, Carina M. Hall, Marielisa Ortiz, Shelby M. Hutton, Ella Santana-Propper, Kimberly R. Celona, Charles H. D. Williamson, Nicole Bratsch, Luis G. V. Fernandes, Joseph D. Busch, Talima Pearson, Sarai Rivera-Garcia, Fred Soltero, Renee Galloway, Jason W. Sahl, Jarlath E. Nally, David M. Wagner

PLoS Negl Trop Dis. 2022 May; 16(5): e0009959. Published online 2022 May 18. doi: 10.1371/journal.pntd.0009959

PMCID:: PMC9154103

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Select item 60101549.

Advances and challenges in barcoding pathogenic and environmental Leptospira

Vanina Guernier, Kathryn J. Allan, Cyrille Goarant

Parasitology. Author manuscript; available in PMC 2018 Jun 20.

Published in final edited form as: Parasitology. 2018 Apr; 145(5): 595–607. Published online 2017 Jul 18. doi: 10.1017/S0031182017001147

PMCID:: PMC6010154

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Select item 593839610.

Biodiversity of Environmental Leptospira: Improving Identification and Revisiting the Diagnosis

Roman Thibeaux, Dominique Girault, Emilie Bierque, Marie-Estelle Soupé-Gilbert, Anna Rettinger, Anthony Douyère, Michael Meyer, Gregorio Iraola, Mathieu Picardeau, Cyrille Goarant

Front Microbiol. 2018; 9: 816. Published online 2018 May 1. doi: 10.3389/fmicb.2018.00816

PMCID:: PMC5938396

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Select item 691367511.

Molecular characterization and phylogenetic analysis of human pathogenic Leptospira species circulating in a tertiary care hospital of Western Uttar Pradesh in India

Md. Mahtab, Fatima Khan, Mohd Azam, Meher Rizvi, Asfia Sultan, Indu Shukla, Ahmad Almatroudi

Pathog Glob Health. 2019 Sep; 113(6): 275–281. Published online 2019 Dec 9. doi: 10.1080/20477724.2019.1685196

PMCID:: PMC6913675

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Select item 658609612.

Identification of Leptospira spp. from environmental sources in areas with high human leptospirosis incidence in the Philippines

Marjo V. Mendoza, Windell L. Rivera

Pathog Glob Health. 2019 May; 113(3): 109–116. Published online 2019 Apr 22. doi: 10.1080/20477724.2019.1607460

PMCID:: PMC6586096

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Select item 573876413.

Characterization of Leptospira isolates from humans and the environment in Uruguay

Paulina Meny, Clara Menéndez, Jair Quintero, Elba Hernández, Cristina Ríos, Ilana Teruszkin Balassiano, Camilla Nunes Dos Reis Trindade, Juliana Magalhães Vital-Brazil, Tatiane Mendes Varela Ramos, Natalia Ashfield, Camila Feble, Esthefani Avila, Felipe Schelotto, Gustavo Varela

Rev Inst Med Trop Sao Paulo. 2017; 59: e79. Published online 2017 Dec 21. doi: 10.1590/S1678-9946201759079

PMCID:: PMC5738764

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Select item 535039014.

Diversity of Leptospira spp. in Rats and Environment from Urban Areas of Sarawak, Malaysia

Chai Fung Pui, Lesley Maurice Bilung, Kasing Apun, Lela Su'ut

J Trop Med. 2017; 2017: 3760674. Published online 2017 Feb 28. doi: 10.1155/2017/3760674

PMCID:: PMC5350390

Article PDF–866K

Select item 1019709915.

Leptospira yasudae sp. nov. and Leptospira stimsonii sp. nov., two new species of the pathogenic group isolated from environmental sources

Arnau Casanovas-Massana, Camila Hamond, Luciane A. Santos, Daiana de Oliveira, Kathryn P. Hacker, Ilana Balassiano, Federico Costa, Marco A. Medeiros, Mitermayer G. Reis, Albert I. Ko, Elsio A. Wunder

Int J Syst Evol Microbiol. 2020; 70(3): 1450–1456. Published online 2019 Jun 11. doi: 10.1099/ijsem.0.003480

PMCID:: PMC10197099

Article PDF–446K

Select item 482067016.

Profiling of Leptospira interrogans, L. santarosai, L. meyeri and L. borgpetersenii by SE-AFLP, PFGE and susceptibility testing—a continuous attempt at species and serovar differentiation

Luisa Z Moreno, Fabiana Miraglia, Walter Lilenbaum, José SF Neto, Julio C Freitas, Zenaide M Morais, Rudy A Hartskeerl, Barbara LP da Costa, Silvio A Vasconcellos, Andrea M Moreno

Emerg Microbes Infect. 2016 Mar; 5(3): e17. Published online 2016 Mar 9. doi: 10.1038/emi.2016.16

PMCID:: PMC4820670

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Select item 661163617.

Genetic characteristics of pathogenic Leptospira in wild small animals and livestock in Jiangxi Province, China, 2002–2015

Cuicai Zhang, Jianmin Xu, Tinglan Zhang, Haiyan Qiu, Zhenpeng Li, Enmin Zhang, Shijun Li, Yung-Fu Chang, Xiaokui Guo, Xiugao Jiang, Yongzhang Zhu

PLoS Negl Trop Dis. 2019 Jun; 13(6): e0007513. Published online 2019 Jun 24. doi: 10.1371/journal.pntd.0007513

PMCID:: PMC6611636

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Select item 248128318.

Conservation of the S10-spc-α Locus within Otherwise Highly Plastic Genomes Provides Phylogenetic Insight into the Genus Leptospira

Berta Victoria, Ahmed Ahmed, Richard L. Zuerner, Niyaz Ahmed, Dieter M. Bulach, Javier Quinteiro, Rudy A. Hartskeerl

PLoS One. 2008; 3(7): e2752. Published online 2008 Jul 16. doi: 10.1371/journal.pone.0002752

PMCID:: PMC2481283

Article PDF–453K

Select item 799977219.

Leptospira fainei Detected in Testicles and Epididymis of Wild Boar (Sus scrofa)

Giovanni Cilia, Fabrizio Bertelloni, Domenico Cerri, Filippo Fratini

Biology (Basel) 2021 Mar; 10(3): 193. Published online 2021 Mar 4. doi: 10.3390/biology10030193

PMCID:: PMC7999772

Article PDF–556K

Select item 747312120.

Creating a library of random transposon mutants in Leptospira

Christopher J. Pappas, Hui Xu, Md A. Motaleb

Methods Mol Biol. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Methods Mol Biol. 2020; 2134: 77–96. doi: 10.1007/978-1-0716-0459-5_8

PMCID:: PMC7473121

Article PDF–1.7M

Did you mean: leptospira meyer (303 items)

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FIG. 4

Proposed pathway for methionine biosynthesis in L. meyeri. MetX, O-acetylhomoserine transferase; MetY, O-acetylhomoserine sulfhydrylase.

Direct Sulfhydrylation for Methionine Biosynthesis in Leptospira meyeri

J Bacteriol. 1998 Jan;180(2):250-255.
Figure 4The pathogenic rtPCR shows blunted amplification of a clinical sample with 16S sequence consistent with a non-pathogenic Leptospira strain.

Amplification curves for a clinical sample with sequence matching the non-pathogenic Leptospira, L. meyeri, L. biflexa, and L. wolbachii (open circles) in the (A) pathogenic rtPCR and (B) UFI assay. Two clinical samples with 16S sequence matching pathogenic strains (solid diamonds) are shown for comparison. The threshold for positivity is set at 0.05 normalized fluorescence units for both assays (dotted red line).

Sensitive Real-Time PCR Detection of Pathogenic Leptospira spp. and a Comparison of Nucleic Acid Amplification Methods for the Diagnosis of Leptospirosis

PLoS One. 2014;9(11):e112356.
Figure 3

Dendrogram showing the relationships among the Leptospira spp. pulsotypes.

Profiling of Leptospira interrogans, L. santarosai, L. meyeri and L. borgpetersenii by SE-AFLP, PFGE and susceptibility testing—a continuous attempt at species and serovar differentiation

Emerg Microbes Infect. 2016 Mar;5(3):e17.
FIG. 3

Immunoblot of a panel of Leptospira species obtained by using LipL32 antiserum. LipL32 antiserum detected a single band in each of the lanes containing pathogenic Leptospira species. LipL32 expression is highly conserved among the pathogenic Leptospira species, L. interrogans, L. kirschneri, L. borgpetersenii, L. inadai, L. noguchii, L. santarosai, and L. weilii. L. biflexa, L. meyeri, and L. wolbachii are nonpathogenic species, as is the related organism Leptonema illini.

The Leptospiral Major Outer Membrane Protein LipL32 Is a Lipoprotein Expressed during Mammalian Infection

Infect Immun. 2000 Apr;68(4):2276-2285.